A group of LMU physicists conduct a study to gain insight to the central question in the origin of life: how can structure emerge from randomness. This research paper shows that linking short oligomers from a random sequence pool in a templated ligation reaction can reduce the sequence of space of product strands. This self-selecting ligation reaction can produce a favorable highly structured, long, and nonrandom sequence pool. This research was inspired by Dieter Braun’s previous research on the Soret effect, RNA strand accumulation, found in narrow, water-filled chambers inside sea volcanic rocks.
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