Aiming at the problem of high wall shear stress at the nozzle of micro extrusion biological 3D printing technology, this paper proposes a method of reducing the viscosity of biological ink through vibration, so as to reduce the shear stress and improve printing efficiency and cell vitality. The 3D bioprinting extrusion device is taken as the research object, and the influence of vibration parameters on the printing process is studied on by fluid structure coupling simulation of the extrusion device.
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