Mice with sloppy proteinmaking machinery grow old faster, study finds. Cells are continually cranking out new proteins, but like car factories, they produce some lemons. A study of mice now suggests these defective proteins speed aging, bolstering an idea first proposed 60 years ago. The new paper “fills a critical gap” and “allows us to say that protein damage is an accelerant of aging,” says molecular biologist Richard Morimoto of Northwestern University, who wasn’t connected to the study.
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